Tetrapyrroles and derivatives
Abcam Dorsomorphin (Compound C), AMP-kinase inhibitor, 5MG
MW 399.5 Da, Purity >99%. Potent, selective and reversible inhibitor of AMP-kinase (Ki = 109 nM). Inhibits AMPK activation induced by AICAR (ab120358) and metformin (ab120847). Selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Does not affect ZAPK, SYK, PKCθ, PKA and JAK3. Cell-permeable. Also available in a water soluble form (Dorsomorphin dihydrochloride - ab144821).
The product is subject to the following: Abcam Restricted Use Statement
Abcam U-69593, kappa1-opioid receptor agonist, 5MG
MW 356.5 Da, Purity >99%. Potent, selective κ1-opioid receptor agonist (EC50 = 80-109 nM). Active *in vivo*. Antinociceptive.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clozapine N-o x ide, Metabolite of Clozapine, 100MG
MW 342.8 Da, Purity >99%. Metabolite of atypical antipsychotic Clozapine (ab120019). Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Research Products International Corp Cyanocobalamin (Vitamin B12), 100 Milligrams
Common vitamin of the Vitamin B12 family.
Medchemexpress LLC Hematoporphyrin monomethyl ether | 148471-91-4 | MFCD32215011 | 95.0% | C70H80N8O12 | 10MG
Hematoporphyrin monomethyl ether is a porphyrin-related photosensitizer used as a research reagent for photodynamic studies. It produces singlet oxygen when activated by light and is commonly applied in photodynamic therapy research, cellular photochemistry, and light-activated imaging experiments.
- Porphyrin-derived photosensitizer with high singlet oxygen yield.
- Suitable for photodynamic therapy research and in vitro photochemistry.
- Solid with a purple to purplish red appearance for easy visual identification.
- Available in small research pack sizes suitable for laboratory experiments.
- Store protected from light and refrigerate to maintain stability.
Abcam SB-277011-A dihydrochloride, D3 antagonist, 5MG
MW 511.5 Da, Purity >98%. Potent, highly selective D3 receptor antagonist (pKi = 7.95 at hD3 receptors). Exhibits over 100-fold selectivity over D2 receptors. Blood-brain barrier (BBB) permeable. Diminishes nicotine, cocaine and alcohol self-administration. Interferes with mechanisms of drug-taking and reinstatement of drug-taking behaviours.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DPDPE, delta opioid receptor agonist, 1MG
MW 645.79 g/mol, Purity >95%. Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GBR 12909 dihydrochloride, Dopamine transport inhibitor, 10MG
MW 523.5 Da, Purity >98%. Potent, selective dopamine reuptake inhibitor (IC₅₀ = 2.32 μM in rat hippocampal slices; IC₅₀ = 6-35 μM in whole cell patch clamp recordings).
The product is subject to the following: Abcam Restricted Use Statement
Frontier Specialty Chemicals 1G MESO-TETRA(PENTAFLUOROPHENY
meso-Tetra(pentafluorophenyl)porphine chlorin free; CAS: 25440-14-6; 1g
Abcam SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist, 10MG
MW 292.33 Da, Purity >99%. Potent and selective 5-HT2B and 5-HT2C serotonin receptor antagonist (pKi values are 7.92 (5-HT2C), 5.78 (5-HT2A), 7.65 (5-HT2B), 1A), 1D), 1E) and 1F). Centrally active following oral administration.
The product is subject to the following: Abcam Restricted Use Statement
Frontier Specialty Chemicals 100MG BILIVERDIN HYDROCHLORIDE
Biliverdin hydrochloride; CAS No: 55482-27-4
Abcam ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist, 5MG
MW 283.41 Da, Purity >99%. Selective protease-activated receptor 2 (PAR2) antagonist (IC₅₀ = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement